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Mu-ming Poo (Chinese: 蒲慕明; born October 31, 1948) is a Chinese neuroscientist. He is the Paul Licht Distinguished Professor Emeritus at the University of California, Berkeley and the Founding Director of the Shanghai-based Institute of Neuroscience (ION) of the Chinese Academy of Sciences (CAS). He was awarded the 2016 Gruber Prize in Neuroscience for his pioneering work on synaptic plasticity. At ION, Poo led a team of scientists that produced the world's first truly cloned primates, a pair of crab-eating macaques called Zhongzhong and Huahua in 2017, using somatic cell nuclear transfer (SCNT).

Poo is academicians of National Academy of Sciences (NAS), Academia Sinica, and CAS.